How many miles does a 2001 nissan frontier with a 3.3 v6 engine with a six inch lift and oversized tires get.?

Take a truck that only gets 17 to 21 mpg and lift it up into the air then install harder to turn tires. Not areodynamic in the first place your gasmilage and engine life may vary. I would suspect less than 13 MPG in town. and around 17 Highway. 3.3 Liter motors and drive train last a long time over 200,000 miles with normal maintence. Clean out the radatatior annually inside and out.